Thermo Fisher Scientific LIPG Polyclonal Antibody, HRP
Human endothelial lipase(LIPG)을 인식하는 HRP 결합 폴리클로날 항체로, Western blot 및 동결 조직 면역조직화학에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태. 마우스 LIPG에는 반응하지 않음.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A C-terminal synthetic peptide made to the human endothelial lipase protein sequence |
| Conjugate | HRP |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_11152164 |
Product Specific Information
This antibody does not react with mouse endothelial lipase.
Target Information
LIPG (Lipase G, Endothelial type) is an endothelial lipase that belongs to the lipoprotein lipase gene family. It is synthesized by endothelial cells and functions at the site of synthesis. LIPG likely plays a physiological role in modulating lipoprotein metabolism. Overexpression of LIPG has been shown to reduce HDL cholesterol levels, while deficiency elevates HDL cholesterol levels in animals. LIPG exhibits substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. It is a member of the TG lipase family, characterized by its lid region providing substrate specificity. LIPG acts as a carboxyl esterase that hydrolyzes high-density lipoproteins, emulsifies triglycerides, aids in fat digestion, and binds to heparin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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