Thermo Fisher Scientific LIPG Polyclonal Antibody, Biotin
Human endothelial lipase(LIPG)에 특이적인 Biotin 결합 Rabbit Polyclonal Antibody. WB, ICC/IF, ELISA에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 0.9 mg/mL 농도. 4°C 암소 보관, 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | - |
| Immunocytochemistry (ICC/IF) | Assay-Dependent | - |
| ELISA | Assay-Dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | An N-terminal synthetic peptide made to the human endothelial lipase protein sequence |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152398 |
Product Specific Information
This antibody does not react with mouse endothelial lipase.
Target Information
LIPG (Lipase G, Endothelial type) is an endothelial lipase and a novel member of the lipoprotein lipase gene family. It is synthesized by endothelial cells and functions locally at the site of synthesis. LIPG plays a physiological role in modulating lipoprotein metabolism. Overexpression of LIPG reduces HDL cholesterol levels, while deficiency elevates HDL cholesterol in animals. LIPG exhibits substantial phospholipase activity and is involved in lipoprotein metabolism and vascular biology. It belongs to the TG lipase family, characterized by its lid region providing substrate specificity. LIPG acts as a carboxyl esterase that hydrolyzes high-density lipoproteins, emulsifies triglycerides, and is essential for efficient digestion of dietary fats and heparin binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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