Thermo Fisher Scientific Human SDPR Synthetic Peptide
인간 SDPR 단백질의 아미노 말단 부위에서 유래한 합성 펩타이드로, PA5-34521 항체의 블로킹 실험에 사용 가능. 정제된 액상 형태이며, PBS 버퍼에 0.1% BSA와 0.02% sodium azide를 포함. 연구용으로만 사용.
- 카탈로그번호
- PEP1564
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to an 18 amino acid sequence near the amino terminus of human SDPR.
PEP-1564 can be used as a blocking peptide with polyclonal antibody PA5-34521.
For use as a blocking peptide in Western blot, incubate the peptide with an equal volume of antibody for 30 minutes at 37°C.
Target Information
The serum deprivation-response protein (SDPR) is a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells.
SDPR is a substrate for protein kinase C (PKC) phosphorylation and recruits the polymerase I and transcript release factor (PTRF) to caveolae.
Loss of SDPR results in caveolae loss, while overexpression leads to caveolae deformation and membrane tubulation.
SDPR, PTRF, and PRKCDBP (another cavin family member) are downregulated in breast cancer cell lines and tissues, suggesting that cavin family protein expression may serve as a prognostic indicator for breast cancer progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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