Thermo Fisher Scientific CD185 (CXCR5) Monoclonal Antibody (MU5UBEE), eBioscience
Human CD185(CXCR5) 인식하는 MU5UBEE 단클론 항체로, Flow Cytometry 및 IHC에 적합. 비결합형 형태이며 다양한 형광 및 효소 결합 옵션 제공. 고순도(>90%)로 제조되어 B세포 및 T세포 분석 연구에 활용 가능.
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Thermo Fisher Scientific CD185 (CXCR5) Monoclonal Antibody (MU5UBEE), eBioscience
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 1 publication |
| Flow Cytometry (Flow) | 0.25 µg/test | View 15 publications |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Non-human primate, Rhesus monkey |
| Published Species | Baboon, Cynomolgus monkey, Human, Rhesus monkey |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MU5UBEE |
| Immunogen | N-terminal extracellular domain of CXCR5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2865363 |
Available Conjugated Formats
- Alexa Fluor 532, 700
- APC, Biotin
- Brilliant UV/Violet/Yellow series (395–810 range)
- eFluor 450, FITC
- NovaFluor Blue/Red/UV/Violet/Yellow series
- PE, PE-Cyanine5, PE-Cyanine7, PE-eFluor 610
- PerCP-eFluor 710
- Super Bright 436, 600, 645, 702
- Request custom conjugation
Product Specific Information
The MU5UBEE monoclonal antibody reacts with human CD185 (CXCR5), also known as Burkitt lymphoma receptor 1 (BLR1). CXCR5 is a seven-transmembrane G protein-coupled receptor expressed in Burkitt’s lymphoma, B cells, and CD4+ T cells (excluding Th1/Th2). It is involved in lymphocyte trafficking and T cell migration into B cell follicles in response to CXCL13, serving as a marker of follicular helper T cells.
Applications Reported: Flow cytometric analysis.
Applications Tested: Flow cytometry on human peripheral blood cells (≤0.25 µg/test, 100 µL volume). Optimal titration recommended.
Purity: >90% (SDS-PAGE).
Aggregation: <10% (HPLC).
Filtration: 0.2 µm post-manufacturing filtered.
Target Information
CXCR5 (C-X-C Chemokine Receptor Type 5, CD185) is a G protein-coupled receptor for chemokine BLC, expressed in Burkitt’s lymphoma and lymphoid tissues. It plays a key role in B cell migration and is found in human blood, lymph nodes, spleen, and other organs. GPCR family members share seven transmembrane helices and are central to signal transduction. CXCR5-related research contributes to understanding immune cell migration and pharmacological targeting of GPCRs.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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