Merck Chondroitinase ABC from Proteus vulgaris

Chondroitinase ABC from Proteus vulgaris

lyophilized powder, 0.3-3 units/mg solid

Chondroitin ABC Lyase

생물학적 소스

bacterial (Proteus vulgaris)

Quality Level

300

form

lyophilized powder

specific activity

0.3-3 units/mg solid

분자량

~120 kDa by gel filtration

구성

Protein, ~35% biuret

application(s)

diagnostic assay manufacturing

저장 온도

−20°C

Chondroitinase ABC from Sigma has been used to digest O-linked chondroitin sulfate-like glycosaminoglycan (CSGAG). The enzyme has also been used to digest glycosaminoglycan chains in proteoglycans during the construction and expression of a recombinant versican gene in mammalian systems. Furthermore, it has been used to digest chondroitin sulfate in the proteoglycan complexes. The enzyme has also been used in the removal of glycan chains from aggrecan, which eliminates the axon growth-inhibitory effect of aggrecan.