Merck Dipeptidylpeptidase human

Dipeptidylpeptidase human

recombinant, expressed in Hi-5 Insect cells, ≥95% (SDS-PAGE)

ADABP, CD26, DPPIV, TP103, Adenosine deaminase complexing protein 2

생물학적 소스

human

재조합

expressed in Hi-5 Insect cells

assay

≥95% (SDS-PAGE)

form

liquid

분자량

86.4 kDa

포장

pkg of 10 μg

농도

0.5 mg/mL

NCBI 수납 번호

P27487

UniProt 수납 번호

P27487

배송 상태

wet ice

저장 온도

−20°C

Gene Information

human ... DPP4(1803)

DPP4 is a serine exopeptidase and complex enzyme that is expressed on the surface of most cell types as an intrinsic membrane glycoprotein that cleaves X-proline dipeptides from the N-terminus of polypeptides and plays a role in t-cell activation. DPP4 is associated with intracellular signal transduction, apoptosis and involved in tumor biology. There are at least 63 substrates which can bind specifically to DPP4 enzyme including growth factors, chemokines, neuro peptides. Furthermore, DPP4 plays a major role in glucose metabolism by cleaving incretins such as glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). DPP4 Human Recombinant is a single, glycosylated polypeptide chain containing 746 amino acids (aa 39-766) with a C-terminal His-tag and is purified using conventional chromatography techniques.