Thermo Fisher Scientific CD355 (CRTAM) Monoclonal Antibody (Cr24.1), PE, eBioscience

Thermo Fisher Scientific CD355 (CRTAM) Monoclonal Antibody (Cr24.1), PE, eBioscience

Applications

• Flow Cytometry (Flow)

Tested Dilution: 5 µL (0.5 µg)/test
Publications: -

Product Specifications

Additional Formats

• Alexa Fluor 488
• APC
• PE-Cyanine7
• Request custom conjugation

Product Specific Information

This monoclonal antibody Cr24.1 reacts with human CD355 (CRTAM), also known as Class-I MHC-restricted T-cell-associated molecule.
CD355 typically exists as a homodimer but can form a heterodimer with its ligand Necl-2. It is transiently expressed by activated NK, NKT, γδT, and CD8+ T cells, as well as Purkinje neurons.

Human CD355 is involved in:

• Immunosurveillance of cancer cells
• γδT cell survival
• Cell polarity and lymphocyte retention in lymph nodes
• Promotion of cytotoxicity in NK cells
• IFN-γ secretion from CD8+ T cells

Cr24.1 has been reported to exhibit antagonist activity.

Applications Reported: Flow cytometric analysis
Applications Tested: Pre-diluted and validated for flow cytometry using stimulated normal human peripheral blood cells.
Use at 5 µL (0.5 µg) per test (100 µL final volume). Recommended cell count: 10⁵–10⁸ cells/test.

Excitation: 488–561 nm
Emission: 578 nm
Compatible Lasers: Blue, Green, Yellow-Green

Target Information

The CRTAM gene is upregulated in CD4⁺ and CD8⁺ T cells and encodes a type I transmembrane protein with V and C1-like Ig domains.

For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.

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