Thermo Fisher Scientific NAGA Polyclonal Antibody
NAGA 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 고순도 항원 친화 크로마토그래피로 정제되었으며, 인간·마우스·랫트 반응성을 보입니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific NAGA Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human NAGA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720186 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
NAGA (N-acetylgalactosaminidase, alpha), also known as alpha-galactosidase B or GALB, is a 411 amino acid lysosomal protein belonging to the glycosyl hydrolase 27 family. It may exist as a homodimer and plays a critical role in glycolipid breakdown.
NAGA encodes alpha-N-acetylgalactosaminidase, a lysosomal enzyme that cleaves alpha-N-acetylgalactosaminyl groups from glycoconjugates.
Mapping to human chromosome 22q13.2, NAGA defects cause an autosomal recessive disorder with three phenotypes known as Schindler disease (types I, II, and III) or NAGA deficiency. Schindler disease type I is the most severe, type III has mild-to-moderate effects, and type II (Kanzaki disease) is characterized by mild intellectual impairment and angiokeratoma corporis diffusum.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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