Thermo Fisher Scientific HNF4A Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human HNF4a (NP_0004483) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HNF4A,uniProtId:P41235-1,ncbiNodeId:9606,antigenRange:100-200,antigenLength:474,antigenImageFileName:PA5-88143_HNF4A_P41235-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88143_HNF4A_P41235-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:HNF4A,uniProtId:P49698-1,ncbiNodeId:10090,antigenRange:1-100,antigenLength:474,antigenImageFileName:PA5-88143_HNF4A_P49698-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88143_HNF4A_P49698-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.09 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804686

Product Specific Information

Positive Samples: Mouse liver; Cellular Location: Nucleus

Immunogen sequence: RQCVVDKDKR NQCRYCRLKK CFRAGMKKEA VQNERDRIST RRSSYEDSSL PSINALLQAE VLSRQITSPV SGINGDIRAK KIASIADVCE SMKEQLLVLV E

Target Information

Hepatocyte nuclear factor 4 alpha (HNF4 alpha) is an orphan nuclear receptor. HNF4a is expressed in the liver, kidney, intestine, and pancreas. Mutation of HNF4a in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1). HNF4 binds to DNA as an exclusive homodimer. The HNF4a gene is alternatively spliced and may generate up to nine different isoforms, HNF4a1 through HNF4a9.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.