Thermo Fisher Scientific RRM1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Immunoprecipitation (IP)

0.5 µg-4 µg antibody for 200 µg-400 µg extracts of

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 593-792 of human RRM1 (NP_0010241) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RRM1,uniProtId:P23921-1,ncbiNodeId:9606,antigenRange:593-792,antigenLength:792,antigenImageFileName:PA5-88145_RRM1_P23921-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88145_RRM1_P23921-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804688

Product Specific Information

Immunogen sequence: IRNSLLIAPM PTASTAQILG NNESIEPYTS NIYTRRVLSG EFQIVNPHLL KDLTERGLWH EEMKNQIIAC NGSIQSIPEI PDDLKQLYKT VWEISQKTVL KMAAERGAFI DQSQSLNIHI AEPNYGKLTS MHFYGWKQGL KTGMYYLRTR PAANPIQFTL NKEKLKDKEK VSKEEEEKER NTAAMVCSLE NRDECLMCGS; Positive Samples: HeLa, MCF7, HT-29, A-549, SW620, Mouse testis, Mouse spleen, Mouse thymus; Cellular Location: Cytoplasm

Target Information

RRM1 (Ribonucleotide reductase M1 polypeptide) is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme which catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. RRM1 is involved in carcinogenesis, tumor progression.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.