
Thermo Fisher Scientific Cystatin C Recombinant Rabbit Monoclonal Antibody (JJ09-16)
Cystatin C 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 IHC(파라핀) 분석에 적합합니다. 높은 특이성과 일관성, 동물 유래 성분이 없는 제형으로 연구용에 최적화되어 있습니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JJ09-16 |
| Immunogen | Recombinant full length protein of Human Cystatin C (aa 1–146) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809752 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
Cystatin C, a member of the type 2 cystatin superfamily, is a potent inhibitor of cysteine proteinases (both endogenous lysosomal cathepsins and pathogenic).
It is a 13 kDa secreted protein found in high concentrations in biological fluids and expressed by all human nucleated cells.
Alterations in Cystatin C levels are associated with cardiovascular diseases such as atherosclerosis, amyloid angiopathy, and myocardial infarction.
Due to its low molecular weight, Cystatin C is also used as a marker for renal failure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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