Thermo Fisher Scientific CDH17 Polyclonal Antibody
CDH17 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 적합합니다. 90 kDa의 내인성 단백질을 검출하며, 순도는 95% 이상입니다. 액상 형태로 제공되며, 4°C 단기 보관 및 -20°C 장기 보관이 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 350–400 of human LI-cadherin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553458 |
Product Specific Information
This antibody detects endogenous protein at a molecular weight of approximately 90 kDa.
Purity is greater than 95% as determined by SDS-PAGE.
Target Information
The CDH17 gene belongs to the cadherin superfamily, encoding calcium-dependent, membrane-associated glycoproteins. The protein is cadherin-like, consisting of seven extracellular cadherin domains and a transmembrane region but lacking the conserved cytoplasmic domain. It is mainly expressed in the gastrointestinal tract and pancreatic ducts, functioning as an intestinal proton-dependent peptide transporter involved in the absorption of peptide-based drugs. CDH17 may also contribute to the morphological organization of the liver and intestine. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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