Thermo Fisher Scientific NFYC Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50–1:200

Product Specifications

Product Specific Information

This antibody detects endogenous NF-YC protein at a molecular weight of 50 kDa.
Purity is >95% by SDS-PAGE.

Target Information

The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y consists of three subunits: NF-YA, NF-YB, and NF-YC. All three are essential for DNA binding. Each NF-Y subunit contains a conserved segment necessary for NF-Y–DNA complex formation, homologous to the histone-fold motif found in eukaryotic histones. The DNA binding domains of NF-YB and NF-YC interact through a histone-fold “handshake” motif similar to the interaction between histone proteins H2B and H2A.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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