Thermo Fisher Scientific SIRT2 Polyclonal Antibody
SIRT2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간과 랫드에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 완충액에 보관되며, 연구용으로만 사용됩니다.
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Applications and Tested Dilution
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human SIRT2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792693 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (90%), Pig (83%), Bovine (84%).
- Positive Control: PC12.
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
The SIRT2 protein (also known as Sirtuin for Silent Mating Type Information 2-Homolog) is a NAD-dependent deacetylase (NDAC) involved in gene silencing, cell cycle regulation, and DNA damage repair.
SIRT2 may function as a tumor suppressor in human gliomas and serve as a molecular marker for these cells.
It also acts as a redox sensor regulating muscle gene expression in response to food intake and exercise, and participates in phosphorylation cascades during mitosis (late G2 phase through cytokinesis).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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