Thermo Fisher Scientific IRF4 Polyclonal Antibody
IRF4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 Immunoprecipitation에 적합합니다. 인간에 반응하며, 마우스·랫·돼지 등에서도 예측 반응성을 보입니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 용액 형태로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunoprecipitation (IP) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human IRF4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792690 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (91%), Rat (92%), Pig (93%), Chicken (87%), Rhesus Monkey (98%), Bovine (93%).
- Positive Control: NCI-H929.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The IRF (interferon regulatory factor) family of transcription factors are characterized by a unique tryptophan pentad repeat DNA-binding domain. The IRFs play a key role in regulating interferons in response to viral infection and in controlling interferon-inducible genes.
IRF4 is lymphocyte-specific and negatively regulates toll-like receptor (TLR) signaling, which is central to both innate and adaptive immune activation.
A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be associated with multiple myeloma. Alternatively spliced transcript variants have been identified.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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