Thermo Fisher Scientific Phospho-MEK3/MEK6 (Ser189, Ser207) Recombinant Rabbit Monoclonal Antibody (MKK3S189MKK6S207-D3)
Phospho-MEK3/MEK6 (Ser189, Ser207) 인산화 단백질을 특이적으로 인식하는 재조합 토끼 단클론 항체. Western blot 및 유세포분석에 적합하며, 높은 특이성과 재현성을 제공. Animal-free 생산 시스템으로 로트 간 일관성이 우수.
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Applications
Western Blot (WB)
- Assay-dependent
Flow Cytometry (Flow)
- 1–1,000 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MKK3S189MKK6S207-D3 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser189 of human phospho MKK3 and Ser207 of human phospho MKK6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745046 |
Additional Formats
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences are cloned from immunoreactive rabbits, and individual clones are screened for optimal performance.
Advantages:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to large rabbit immune repertoire
Target Information
This gene encodes a dual specificity protein kinase (MAP kinase kinase) involved in the p38 MAP kinase signaling pathway. It phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress, playing a key role in stress-induced cell cycle arrest, transcription activation, and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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