Thermo Fisher Scientific Phospho-MEK1/MEK2 (Ser221) Recombinant Rabbit Monoclonal Antibody (MEK12S221-D3)

Applications

Western Blot (WB)

• Assay-dependent

Flow Cytometry (Flow)

• 1–1,000 ng/mL

Product Specifications

Additional Formats

• APC
• FITC
• PE
• Request custom conjugation

Product Specific Information

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, followed by screening to select optimal production candidates.
Advantages include:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broader immunoreactivity due to the larger rabbit immune repertoire

Target Information

MEK1 (MAP Kinase Kinase, also known as MKK) is a key component of the MAP kinase cascade that regulates cell growth and differentiation (Ahn, 1993; Chong et al., 2003).
In the brain, this pathway plays an essential role in synaptic function (Adams and Sweatt, 2002).
Activated MEK1 acts as a dual-specificity kinase phosphorylating threonine and tyrosine residues on MAP kinase (Kyriakis et al., 1991; Seger et al., 1991; Crews et al., 1992).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

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