Thermo Fisher Scientific Phospho-MEK1 (Ser298) Recombinant Rabbit Monoclonal Antibody (MEK1S298-H8), APC
Phospho-MEK1 (Ser298)을 인식하는 재조합 토끼 단클론 항체로, APC 형광표지되어 Flow Cytometry에 적합합니다. 높은 특이성과 재현성을 제공하며, 인간 및 랫트 시료에 반응합니다. 단백질 A/G로 정제되어 안정적이며 4°C에서 보관 가능합니다.
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Applications and Tested Dilution
- Application: Flow Cytometry (Flow)
- Tested Dilution: 0.1–1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MEK1S298-H8 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser298 of human phospho MEK1 |
| Conjugate | APC |
| Excitation/Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745044 |
Additional Formats
- Unconjugated (MA5-37069)
- FITC (MA5-37071)
- PE (MA5-37070)
- Custom conjugation available upon request
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
MAP2K1 (MEK1) kinase is a dual-specificity protein kinase functioning in MAPK cascades to control cell growth and differentiation. It is activated by phosphorylation at Ser218 and Ser222 by Raf1 and participates in stress response, apoptosis, and cytokine-induced proliferation. Mutations may cause cardiofaciocutaneous syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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