Thermo Fisher Scientific COL17A1 Polyclonal Antibody
Human COL17A1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 IHC(P) 검증 완료. 합성 펩타이드(aa 481–530)로부터 유래. 액상형, 1 mg/mL 농도, PBS/glycerol 버퍼에 보관. 연구용으로만 사용 가능.
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- PA568452
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:300 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human COL17A1 (aa 481–530) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2692097 |
Product Specific Information
Predicted to react with Human samples.
Target Information
COL17A1 is the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein and a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane.
COL17A1 is a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). It is localized to tissues containing type I collagen and may help maintain the integrity of the extracellular matrix.
Diseases associated with COL17A1 dysfunction include epithelial recurrent erosion dystrophy and epidermolysis bullosa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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