Thermo Fisher Scientific KIR3DL2 Polyclonal Antibody
Human KIR3DL2 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50–1:300 희석 비율로 사용 가능. 비결합형 액상 형태이며, 고순도 친화 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
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- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:300
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human KIR3DL2 (aa 221–270) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2688422 |
Product Specific Information
Predicted to react with Human samples.
Target Information
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous, located on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC).
The KIR gene cluster varies among haplotypes, though several framework genes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2) are common to all.
KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by the length of the cytoplasmic domain (L or S).
Proteins with long cytoplasmic domains transduce inhibitory signals via immune tyrosine-based inhibitory motifs (ITIM), whereas those with short domains lack ITIM and instead associate with TYRO protein tyrosine kinase binding protein to transduce activating signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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