Thermo Fisher Scientific CD16 Monoclonal Antibody (3G8), PE-Cyanine7
CD16 단백질을 인식하는 마우스 단클론 항체로, PE-Cyanine7 형광으로 표지되어 있습니다. 인간 및 비인간 영장류 시료의 NK 세포 분석에 적합합니다. 4 µL/10⁶ 세포로 유세포분석(Flow Cytometry)에 사용됩니다. 액상 형태로 4°C 보관하며 동결 금지입니다.
- 카탈로그번호
- MA538693
- 판매단위
- pk
카탈로그
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Applications
- Flow Cytometry (Flow): 4 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3G8 |
| Immunogen | Human neutrophils |
| Conjugate | PE-Cyanine7 |
| Excitation / Emission Max | 569 / 780 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898605 |
Additional Formats
- Unconjugated
- Alexa Fluor 488
- Alexa Fluor 647
- Alexa Fluor 700
- APC
- APC-Cyanine7
- Biotin
- DyLight 594
- FITC
- PE
- PE-Cyanine5
- PerCP
- PerCP-Cyanine5.5
- Request custom conjugation available
Product Specific Information
This antibody detects both 158V and 158F allotypes on natural NK cells.
Target Information
CD16 encodes a receptor that recognizes the Fc portion of immunoglobulin G and is involved in the clearance of immune complexes from the circulation. It also mediates cellular cytotoxicity and can enhance viral infection processes.
The gene FCGR3A shares high similarity with FCGR3B, both located on chromosome 1.
- FCGR3A: Expressed on NK cells as a transmembrane glycoprotein
- FCGR3B: Expressed on polymorphonuclear neutrophils (PMN) with a phosphatidylinositol linkage
Mutations in FCGR3A are associated with immunodeficiency 20 and susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia.
Alternative splicing results in multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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