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Thermo Fisher Scientific CD16 Monoclonal Antibody (3G8), PE-Cyanine5
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Thermo Fisher Scientific CD16 Monoclonal Antibody (3G8), PE-Cyanine5

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인간 및 비인간 영장류 반응성을 가진 CD16 단클론 항체로, PE-Cyanine5 형광 표지. NK 세포 표면의 CD16 인식에 사용되며, 세포독성 및 면역복합체 제거 연구에 적합. 액상 형태로 제공되며 4°C 암소 보관.

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마지막 업데이트 2025. 08. 04. 오후 05:52
Thermo Fisher Scientific MA538692 CD16 Monoclonal Antibody (3G8), PE-Cyanine5 100 tests pk판매 단위 pk ·
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528,900원VAT 포함 581,790원

Thermo Fisher Scientific · Thermo Fisher Scientific CD16 Monoclonal Antibody (3G8), PE-Cyanine5

Applications

  • Flow Cytometry (Flow): 4 µL / 1×10⁶ cells

Product Specifications

항목 내용
Species Reactivity Human, Non-human primate
Host / Isotype Mouse / IgG1, kappa
Class Monoclonal
Type Antibody
Clone 3G8
Immunogen Human neutrophils
Conjugate PE-Cyanine5
Excitation / Emission Max 568 / 666 nm
Form Liquid
Concentration Not determined
Purification Size-exclusion chromatography
Storage buffer PBS with 0.2% BSA
Contains 15 mM sodium azide
Storage conditions 4°C, store in dark, DO NOT FREEZE
Shipping conditions Ambient (domestic); Wet ice (international)
RRID AB_2898604

Additional Formats

  • Unconjugated
  • Alexa Fluor 488
  • Alexa Fluor 647
  • Alexa Fluor 700
  • APC
  • APC-Cyanine7
  • Biotin
  • DyLight 594
  • FITC
  • PE
  • PE-Cyanine7
  • PerCP
  • PerCP-Cyanine5.5
  • Custom conjugation available

Product Specific Information

This antibody detects both 158V and 158F allotypes on natural NK cells.

Target Information

CD16 encodes a receptor that recognizes the Fc portion of immunoglobulin G and is involved in immune complex clearance, cellular cytotoxicity, and enhancement of viral infections.
The FCGR3A gene shares high similarity with FCGR3B on chromosome 1.

  • FCGR3A: Expressed on NK cells, membrane-anchored via transmembrane peptide
  • FCGR3B: Expressed on polymorphonuclear neutrophils (PMN), anchored via PI linkage

Mutations in FCGR3A are associated with:

  • Immunodeficiency 20
  • Susceptibility to recurrent viral infections
  • Systemic lupus erythematosus
  • Alloimmune neonatal neutropenia

Alternatively spliced variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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