Thermo Fisher Scientific CD14 Monoclonal Antibody (MEM-15), PE
인간 및 비인간 영장류 CD14 인식 단클론 항체로, PE로 표지되어 유세포분석(Flow Cytometry)에 적합합니다. 액상 형태로 제공되며, PBS(pH 7.4)와 0.2% BSA, 15mM sodium azide를 포함합니다. 4°C 암소 보관, 동결 금지. 연구용 전용.
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Applications
- Flow Cytometry (Flow): 20 µL / 100 µL whole blood or 10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-15 |
| Immunogen | Human urinary proteins from the urine of a patient suffering from proteinuria |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1071277 |
Additional Formats
- Unconjugated (MA1-19223)
- Biotin (MA1-19514)
- FITC (MA1-19592)
- Custom conjugation available upon request
Product Specific Information
This antibody reacts with soluble forms of CD14 found in serum and in the urine of some nephrotic patients.
Target Information
CD14 is a 55 kDa GPI-anchored glycoprotein constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. It functions as a multifunctional lipopolysaccharide (LPS) receptor and is released into serum in both secreted and enzymatically cleaved forms. CD14 binds LPS in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. Soluble CD14 (sCD14) can discriminate structural differences between LPS molecules and is important for neutralizing serum lipopolysaccharides. CD14 also binds apoptotic cells and influences allergic, inflammatory, and infectious processes. Alternative splicing results in multiple transcript variants encoding the same isoform. CD14 dysfunction is associated with conditions such as Mycobacterium chelonae infection and Croup.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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