Thermo Fisher Scientific CD19 Monoclonal Antibody (LT19), PE
CD19 단백질을 인식하는 마우스 단클론 항체로, PE 형광체로 표지되어 있습니다. 인간 B 림프구 및 여포 수지상세포 표면 항원 검출에 적합합니다. 유세포분석(Flow Cytometry)에 최적화되어 있으며, 다양한 형광체 형식으로도 제공됩니다.
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Applications
- Flow Cytometry (Flow): 20 µL per 100 µL whole blood or 10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LT19 |
| Immunogen | Daudi human Burkitt lymphoma cell line |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, Do Not Freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1071436 |
Additional Formats
- Unconjugated (MA1-19242)
- APC (MA1-19467)
- Biotin (MA1-19517)
- FITC (MA1-19595)
- PerCP (MA1-10127)
- Custom conjugation available upon request
Product Specific Information
This antibody reacts with an extracellular epitope of CD19 (B4), a 95 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on B lymphocytes and follicular dendritic cells. Expression is lost on plasma cells.
Target Information
CD19 is a member of the immunoglobulin superfamily with two Ig-like domains. It is expressed on nearly all peripheral B cells and certain myeloid leukemia cells. CD19 serves as a signal-amplifying coreceptor for the B cell receptor (BCR), regulating B cell proliferation and differentiation. Mutations in CD19 can lead to hypogammaglobulinemia, while overexpression causes B cell hyperactivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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