Thermo Fisher Scientific ATP13A2 Polyclonal Antibody

Applications

Product Specifications

Product Specific Information

Suggested positive control: human and mouse brain membrane prep lysate.

Target Information

Neurodegenerative disorders such as Parkinson and Alzheimer disease cause motor and cognitive dysfunction and belong to a heterogeneous group of common and disabling disorders. ATP13A2, otherwise known as PARK9, is a neuronal P-type ATPase gene underlying an autosomal recessive form of early-onset parkinsonism with pyramidal degeneration and dementia. ATP13A2 protein is located in the membrane of lysosomes and is expressed most strongly in the brain, particularly in the substantia nigra, a region central to Parkinson’s disease.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.