Thermo Fisher Scientific Phospho-CaMKII beta/gamma/delta (Thr287) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human CAMK2B(Accession Q13554), corresponding to amino acid residues around phosphorylated Thr287. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CaMKII beta/gamma/delta,uniProtId:Q13554-1,ncbiNodeId:9606,antigenRange:287,antigenLength:666,antigenImageFileName:PA5-104990_CaMKII_betagammadelta_Q13554-1_Rabbit.svg,antigenImageFileNamePDP:PA5-104990_CaMKII_betagammadelta_Q13554-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:CaMKII beta/gamma/delta,uniProtId:Q13555-1,ncbiNodeId:9606,antigenRange:287,antigenLength:558,antigenImageFileName:PA5-104990_CaMKII_betagammadelta_Q13555-1_Rabbit.svg,antigenImageFileNamePDP:PA5-104990_CaMKII_betagammadelta_Q13555-1_Rabbit_PDP.jpeg,sortOrder:2},{targetFamily:CaMKII beta/gamma/delta,uniProtId:Q13557-1,ncbiNodeId:9606,antigenRange:287,antigenLength:499,antigenImageFileName:PA5-104990_CaMKII_betagammadelta_Q13557-1_Rabbit.svg,antigenImageFileNamePDP:PA5-104990_CaMKII_betagammadelta_Q13557-1_Rabbit_PDP.jpeg,sortOrder:3}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2816463

Product Specific Information

Antibody detects endogenous levels of CaMK2 beta/ gamma/ delta only when phosphorylated at Threonine 287.

Target Information

The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+ and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes, designated alpha, beta, gamma and delta, which may or may not be coexpressed in the same tissue type. CaMKIV is stimulated by Ca2+ and CaM but also requires phosphorylation by a CaMK for full activation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.