Thermo Fisher Scientific SEMA3A Monoclonal Antibody (M317)
Sema3A 단백질을 인식하는 Mouse IgG1 단일클론 항체로 인간, 마우스, 랫트 시료에 반응합니다. Western blot에 1:500 희석으로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 신경 발달 및 질환 관련 연구용으로 적합합니다.
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Thermo Fisher Scientific SEMA3A Monoclonal Antibody (M317)
Applications
- Western Blot (WB): 1:500 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | M317 |
| Immunogen | Clone M317 was generated from a synthetic peptide (coupled to carrier protein) corresponding to amino acids in the central region of human Sema3A. The sequence used is highly conserved in rat and mouse Sema3A, and has low homology to other semaphorin family members. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2942713 |
Product Specific Information
This antibody detects a 95 kDa protein corresponding to the apparent molecular mass of Sema3A on SDS-PAGE immunoblots of human recombinant Sema3A and adult mouse brain lysates.
Target Information
This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type domain, a PSI domain, and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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