Thermo Fisher Scientific Phospho-p73 (Tyr99) Polyclonal Antibody
Phospho-p73 (Tyr99) 특이적 인식 폴리클로날 항체로 인간, 마우스, 랫트 반응성. Western blot 및 IHC(P) 적용 가능. 1 mg/mL 농도의 액상 형태, PBS/glycerol buffer에 보관. DNA 손상 반응 관련 p73 인산화 상태 검출에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TP73 (Accession O15350), corresponding to amino acid residues around phosphorylated Tyr99 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816171 |
Product Specific Information
Antibody detects endogenous levels of p73 only when phosphorylated at Tyrosine 99.
Target Information
P73 (TP73) participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, while isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May act as a tumor suppressor protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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