Thermo Fisher Scientific FCAR Polyclonal Antibody
Rabbit polyclonal antibody against human FCAR, validated for Western blot. Affinity-purified with >95% purity. Recognizes Fc receptor for IgA involved in immune defense. Suitable for research use only.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human FCAR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2719309 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% as determined by SDS-PAGE.
Target Information
The FCAR gene encodes a receptor for the Fc region of IgA and belongs to the immunoglobulin gene superfamily. This transmembrane glycoprotein is expressed on myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils. It mediates immune responses to pathogens by interacting with IgA-opsonized targets and triggering defense processes including:
- Phagocytosis
- Antibody-dependent cell-mediated cytotoxicity
- Release of inflammatory mediators
Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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