Thermo Fisher Scientific CDKL5 Polyclonal Antibody
CDKL5 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 사람, 생쥐, 랫트에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용되며 고순도(>95%)를 제공합니다.
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Thermo Fisher Scientific CDKL5 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:1,000
Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human CDKL5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719311 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
CDKL5 serine/threonine kinase (STK9) is associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome and Rett syndrome (RTT).
CDKL5 regulates nuclear speckle morphology by controlling the phosphorylation state of splicing regulatory proteins and may be indirectly involved in pre-mRNA processing by modulating splicing factor dynamics.
Mutations in CDKL5 are a major cause of infantile spasms and early epileptic seizures in female patients, and later intractable seizure disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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