Thermo Fisher Scientific TYMP Monoclonal Antibody (OTI5B5), TrueMAB
인간 TYMP 단백질을 인식하는 마우스 단클론 항체로 Western Blot 및 IHC(P) 실험에 적합. 고순도 친화 크로마토그래피 정제, 무보존제 제형. 연구용으로만 사용 가능하며 재결합 및 결합 실험에 활용 가능.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5B5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 311–482 of human TYMP produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Thymidine phosphorylase (TP), also known as platelet-derived endothelial growth factor (PD-ECGF) or gliostatin, catalyzes the reversible phosphorolytic cleavage of thymidine and deoxyuridine to their respective bases and 2-deoxyribose-1-phosphate.
It acts as a chemotactic and mitogenic factor for endothelial cells and serves as a non-heparin binding angiogenic factor found in platelets.
Additionally, it plays a role in converting fluoropyrimidines, cytotoxic agents used in cancer therapy, into active metabolites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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