Thermo Fisher Scientific TYMP Monoclonal Antibody (OTI4D4), TrueMAB
Human TYMP 단백질(Thymidine Phosphorylase)을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 적합. Lyophilized 형태이며, PBS buffer(8% trehalose)로 보관. 재구성 후 1 mg/mL 농도, 연구용으로 사용.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D4 |
| Immunogen | Human recombinant protein fragment (aa 311–482 of human TYMP, produced in E. coli) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Thymidine phosphorylase (TP), also known as platelet-derived endothelial growth factor (PD-ECGF) or gliostatin, catalyzes the reversible phosphorolytic cleavage of thymidine and deoxyuridine into their corresponding bases and 2-deoxyribose-1-phosphate.
It acts as a chemotactic and mitogenic factor for endothelial cells and serves as a non-heparin-binding angiogenic factor found in platelets.
Additionally, it plays a role in the transformation of fluoropyrimidines—cytotoxic agents used in cancer treatment—into active cytotoxic metabolites.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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