Thermo Fisher Scientific Cystatin C Polyclonal Antibody
Rat Cystatin C에 특이적인 Sheep Polyclonal Antibody로 Western blot, IHC, IP 등 다양한 응용 가능. 높은 순도(항원 친화 크로마토그래피 정제)와 낮은 교차반응성 제공. PBS 및 trehalose 기반 보존, 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–10 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 5–15 µg/mL |
| Immunoprecipitation (IP) | 25 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant rat Cystatin C (Met1–Ala140) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609410 |
Product Specific Information
- In direct ELISAs, approximately 30% cross-reactivity with recombinant mouse Cystatin C and approximately 15% cross-reactivity with recombinant human Cystatin C is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Cystatin C, a member of the type 2 cystatin superfamily, is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins) and pathogenic.
It is a 13 kDa secreted protein found in high concentrations in biological fluids and expressed by all human nucleated cells.
Altered Cystatin C levels have been associated with cardiovascular diseases such as atherosclerosis, amyloid angiopathy, and myocardial infarction.
Due to its low molecular weight, Cystatin C is also used as a marker of renal failure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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