
Thermo Fisher Scientific HES5 Polyclonal Antibody
HES5 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간·마우스·랫트 시료에 반응. WB 및 IHC(P) 실험에 적합하며, Protein A로 정제된 액상형 제품. 장기 보관 시 -20°C에서 안정적으로 유지.
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Applications
Western Blot (WB)
- Tested Dilution: 6–9 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A portion of amino acid 1–50 of human HES5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2540998 |
Target Information
Hairy and Enhancer-of-split homologues 5 (HES5) is a helix-loop-helix transcriptional factor that negatively regulates cell differentiation during embryogenesis. It contains one basic helix-loop-helix (bHLH) domain and one Orange domain. HES5 acts as a downstream effector of the Notch Signaling Pathway and is expressed in advanced ovarian serous adenocarcinomas and cervical squamous carcinoma. It is also abundantly expressed in osteoarthritis along with Notch1 and Jagged1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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