Thermo Fisher Scientific CACTIN Polyclonal Antibody
CACTIN 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체입니다. Western blot 및 IHC(Paraffin) 실험에 적합하며, 다양한 종에 반응합니다. Protein A로 정제된 액상 형태로 제공되며, PBS/BSA buffer에 보존되어 안정적인 장기 저장이 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 5–7 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Human, Non-human primate, Pig |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A portion of amino acid 460–510 of human Cactin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2541000 |
Target Information
Cactin is a novel negative regulator of TLR signaling and reveals its capacity to target MHC Class III genes at the molecular and functional level. It is localized to the nucleus, which is critical for manifesting its inhibitory effects on TLR signaling. Experimental evidence shows overexpression of Cactin suppresses TLR-induced activation of NF-kB and interferon-regulatory factor transcription factors and induction of TLR-responsive genes. It is also reported that Cactin interacts with IkB-like protein and targets other proteins encoded by genes in the MHC Class III region of chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-23500_CACTIN_Q8WUQ7-1_Rabbit.svg, PA5-23500_CACTIN_Q8WUQ7-1_Rabbit_PDP.jpeg)
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