Thermo Fisher Scientific NFKBIL1 Polyclonal Antibody
Rabbit polyclonal antibody against NFKBIL1 protein for Western blot. Reacts with multiple species including human and primate. Supplied as liquid, 0.5 mg/mL, purified by Protein A. Recommended positive control: HeLa cells. For research use only.
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- PA523499
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Applications
- Western Blot (WB): 2–4 µg/mL
- Suggested positive control: HeLa cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Amphibian, Bovine, Dog, Chimpanzee, Horse, Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (331 RRYLRVQQVRWHPDRFLQR 349) of NFKBIL1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2540999 |
Target Information
NF-kappa-B inhibitor-like protein 1 (NFKBIL1), also known as Ikb-like or IkbL1, is a 381 amino acid member of the inhibitor of NF-kappaB (IkappaB) family. NFKBIL1 contains two ANK repeats and is expressed in the rheumatoid synovial lining and sub-lining layers, co-localized in CD68+ and CD3+ cells but not in Factor VIII+ cells. Defects in NFKBIL1 expression are associated with susceptibility to rheumatoid arthritis (RA), a systemic inflammatory disease with autoimmune features affecting joints, characterized by inflammatory changes in synovial membranes and articular structures, fibrinoid degeneration of collagen fibers, and atrophy of bony structures.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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