Thermo Fisher Scientific Prosapip1 Polyclonal Antibody
Prosapip1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot 및 IHC에 사용 가능하며, Human, Mouse, Rat에 반응합니다. 항원 친화 크로마토그래피로 정제되었으며, SK-N-SH cell lysate를 양성 대조로 권장합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (IHC) | 2.5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide from near the carboxy terminus of human Prosapip1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11151967 |
Product Specific Information
A suggested positive control is SK-N-SH cell lysate.
PA5-20816 can be used with blocking peptide PEP-0930.
Target Information
Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses.
It is thought to bind ProSAP2/Shank3 through a PDZ domain and link it to the Spine-associated Rap-Gap (SPAR).
Prosapip1 shares significant homology with PSD-Zip70, both coding for a Fez1 domain found in four related proteins forming the Fezzins family.
Recent studies show Prosapip1 can be found in endocrine cells, primarily localized in the hormone-storing compartment, suggesting possible roles in non-neuronal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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