Thermo Fisher Scientific ATF4 Monoclonal Antibody ([N360A/24), PerCP

Applications

Product Specifications

Additional Formats

• Unconjugated
• FITC
• PE
• Request custom conjugation

Product Specific Information

• 86% identical to rat, and 85% identical to mouse; <50% identity with ATF5
• 1 µg/mL of MA5-45649 detects ATF4 in 20 µg of rat brain lysate by colorimetric immunoblot using Goat anti-mouse IgG:HRP as secondary antibody
• Detects approximately 60 kDa; does not cross-react with ATF5
• Formerly sold as clone S360A-24

Target Information

This gene encodes a transcription factor originally identified as a mammalian DNA-binding protein that binds the tax-responsive enhancer element in the LTR of HTLV-1. It is also known as cAMP-response element binding protein 2 (CREB-2).
The encoded protein belongs to a family of DNA-binding proteins that includes AP-1, CREBs, and CREB-like proteins, sharing a leucine zipper region for protein-protein interactions and a basic DNA-binding domain.
Two alternative transcripts encode the same protein. Two pseudogenes are located on the X chromosome at q28 within a large inverted duplication region.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지