Thermo Fisher Scientific LRRK2 Monoclonal Antibody (N138/6), APC

Thermo Fisher Scientific LRRK2 Monoclonal Antibody (N138/6), APC

Applications and Tested Dilution

Species Reactivity

Human, Mouse, Rat

Host / Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

N138/6

Immunogen

Fusion protein, amino acids 1–500 (N-terminus) of human LRRK2.

Conjugate

APC (Allophycocyanin)

Additional formats available:

• FITC
• PerCP
• Request custom conjugation

Excitation / Emission Max

651 / 660 nm
(Refer to spectra viewer for detailed fluorescence profile)

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage Buffer

95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA

Contains

No preservative

Storage Conditions

4°C

Shipping Conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2932098

Product Specific Information

• 83% identical in mouse and rat; no significant identity with LRRK1.
• 1 µg/mL of MA5-45644 detects LRRK2/Dardarin in 20 µg rat brain lysate by colorimetric immunoblot using Goat anti-mouse IgG:HRP as secondary antibody.
• Detects >200 kDa.
• Formerly sold as clone S138-6.

Target Information

LRRK2 (Leucine-rich repeat kinase 2) is a multidomain protein containing kinase, GTPase, and leucine-rich repeat domains. Mutations in LRRK2 are linked to Parkinson’s disease. It is mainly cytoplasmic but also associates with the mitochondrial outer membrane.

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For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.

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