Thermo Fisher Scientific Phospho-Acetyl-CoA Carboxylase (Ser80) Polyclonal Antibody
Phospho-Ser80 부위의 Acetyl-CoA Carboxylase(ACC1)를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF에 적합. 인산화된 ACC1만 검출하며, 지방산 합성 연구에 활용 가능.
- 카탈로그번호
- PA5104981
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-Acetyl-CoA Carboxylase (Ser80) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Item | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ACACA (Accession Q13085), corresponding to amino acid residues around phosphorylated Ser80. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816454 |
Product Specific Information
This antibody detects endogenous levels of ACC1 only when phosphorylated at Ser80 (historically referenced as Ser79).
Target Information
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system and a biotin-containing enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA — the rate-limiting step in fatty acid synthesis.
There are two ACC forms, alpha and beta, encoded by distinct genes. ACC-alpha is highly enriched in lipogenic tissues.
The enzyme is regulated both long-term (transcriptional and translational control) and short-term (phosphorylation/dephosphorylation of serine residues and allosteric regulation by citrate or palmitoyl-CoA).
Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.