Thermo Fisher Scientific ATP7B Monoclonal Antibody (L62/29), APC
ATP7B 단백질을 인식하는 마우스 단일클론 항체로 APC 형광체가 결합되어 있습니다. Western blot, IHC, ICC/IF, IP 등 다양한 응용에 사용 가능하며 인간, 생쥐, 랫트 반응성을 보입니다. 단백질 G 정제, 1 mg/mL 농도, 4°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | L62/29 |
| Immunogen | Synthetic peptide amino acids 3–21 (cytoplasmic N-terminus) of human Copper-transporting ATPase2 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931976 |
Additional Formats
- Unconjugated (MA5-27719)
- FITC (MA5-45523)
- PE (MA5-45525)
- PerCP (MA5-45524)
- Request custom conjugation (Form link)
Product Specific Information
1 µg/mL of MA5-45522 was sufficient for detection of Copper-transporting ATPase2 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat IgG:HRP as the secondary antibody.
Detects approximately 160 kDa in rat brain membrane preparations.
This antibody was formerly sold as clone S62-29.
Target Information
ATP7B gene encodes a P-type cation transport ATPase with multiple membrane-spanning domains, an ATPase consensus sequence, hinge domain, phosphorylation site, and copper-binding sites.
It functions as a monomer exporting copper out of cells, such as hepatic copper efflux into bile.
Alternate splice variants yield isoforms with distinct localizations.
Mutations are associated with Wilson disease (WD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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