Thermo Fisher Scientific PRDX6 Monoclonal Antibody (1A11)
PRDX6 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, ICC/IF, ELISA, IP 등 다양한 응용에 적합합니다. Mouse IgG1 형식의 비표지 항체이며, HeLa 세포를 양성 대조군으로 권장합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 20 µL/mL |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | 2 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A11 |
| Immunogen | Purified, recombinant, human peroxiredoxin 4 protein expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_1086596 |
Product Specific Information
A suggested positive control for this product is HeLa cells.
Target Information
Peroxiredoxin (Prx) is a growing peroxidase family involved in cell proliferation, differentiation, and apoptosis. Mammalian Prx proteins are classified into typical 2-Cys, atypical 2-Cys, and 1-Cys Prx subgroups. Prx VI belongs to the 1-Cys Prx subgroup, while the other five 2-Cys Prx isotypes exhibit thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20–30 kDa in size and vary in subcellular localization: Prx I, II, and VI are found in the cytosol; Prx III in mitochondria; Prx IV in the ER and secretory pathways; and Prx V is distributed in peroxisome, mitochondria, and cytosol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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