Thermo Fisher Scientific TrxR1 Monoclonal Antibody (5A5)
Thioredoxin reductase 1 단백질을 인식하는 Mouse monoclonal antibody(클론 5A5). Western blot, ELISA, Immunoprecipitation에 사용 가능. HeLa 세포에서 양성 대조군으로 추천. 산화 스트레스 보호 및 셀레늄 대사 연구에 적합.
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Applications 및 권장 희석 배수
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 1 publication |
| ELISA | Assay-dependent | - |
| Immunoprecipitation (IP) | 1–2 µL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published Species | Bovine |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5A5 |
| Immunogen | Purified, recombinant, human thioredoxin reductase 1 protein expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2210231 |
Product Specific Information
A suggested positive control for this product is HeLa cells.
Target Information
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer that uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3′ UTR of selenocysteine-containing genes has a common stem-loop structure, the SECIS element, necessary for recognition of UGA as a Sec codon rather than a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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