Thermo Fisher Scientific TrxR1 Monoclonal Antibody (19A1)
TrxR1 단백질을 인식하는 Mouse IgG1 단클론 항체. Western blot, ICC/IF, Flow cytometry, ELISA, IP 등 다양한 응용 가능. HeLa 세포를 양성 대조로 권장. 인간 유래 단백질에 특이적이며 산화 스트레스 연구에 유용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:5,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:250 | - |
| Flow Cytometry (Flow) | 1:20 | - |
| ELISA | Assay-dependent | - |
| Immunoprecipitation (IP) | 1–2 µL | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 19A1 |
| Immunogen | Purified, recombinant, human thioredoxin reductase 1 protein expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2210232 |
Product Specific Information
A suggested positive control for this product is HeLa cells.
Target Information
This gene encodes a member of the pyridine nucleotide oxidoreductase family. The protein reduces thioredoxins and other substrates, playing a role in selenium metabolism and protection against oxidative stress. The functional enzyme is a homodimer using FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue required for catalytic activity, encoded by the UGA codon that typically signals translation termination. The 3′ UTR of selenocysteine-containing genes includes a SECIS element necessary for recognizing UGA as a Sec codon rather than a stop signal. Alternative splicing produces several transcript variants encoding identical or distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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