Thermo Fisher Scientific JunD Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

10 µg/mL

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

2-3 µg/mL

-

ChIP assay (ChIP)

1-3 µL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues G(329) C Q L L P Q H Q V P A Y(341) of mouse JunD. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:JunD,uniProtId:P15066-1,ncbiNodeId:10090,antigenRange:330-341,antigenLength:341,antigenImageFileName:PA1-834_JunD_P15066-1_Rabbit.svg,antigenImageFileNamePDP:PA1-834_JunD_P15066-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

3.04 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2249440

Product Specific Information

PA1-834 detects JunD from mouse cells.

PA1-834 has been successfully used in Western blot and ChIP procedures. By Western blot, this antibody detects proteins from ~37-41 kDa representing JunD from both un-induced and induced mouse NIH 3T3 cells.

The PA1-834 immunogen is a synthetic peptide corresponding to residues G(329) C Q L L P Q H Q V P A Y(341) of mouse JunD. This sequence is comletely conserved between mouse, human and rat.

Reconstitute with PBS.

Target Information

JunD is a transcription factor which is coded by JunD gene. JunD transcriptional activity is modulated by phosphorylation in response to cellular stress via the c-Jun N terminal kinase (JNK)/Stress-Activated Protein Kinase (SAPK) family of protein kinase. Jun proteins are capable of forming dimers with Fos, ATF and CREB family transcription factors to form the AP-1 complex that differentially regulates a variety of target genes involved in cellular growth, proliferation, differentiation and apoptosis. Also, JunD plays an important role in metabolism via modulation of IGF-1 signaling pathway.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.