Thermo Fisher Scientific JunD Polyclonal Antibody
JunD 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, ICC/IF, ChIP assay에 적합. Human, Mouse, Rat에 반응하며, 합성 펩타이드 면역원 사용. 동결건조 형태로 제공되며, PBS로 재구성 후 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 10 µg/mL | View 1 publication |
| Immunocytochemistry (ICC/IF) | 2–3 µg/mL | - |
| ChIP assay (ChIP) | 1–3 µL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues G(329) C Q L L P Q H Q V P A Y(341) of mouse JunD |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 3.04 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2249440 |
Product Specific Information
- PA1-834 detects JunD from mouse cells.
- Successfully used in Western blot and ChIP procedures.
- Detects proteins of approximately 37–41 kDa representing JunD from both uninduced and induced mouse NIH 3T3 cells.
- The immunogen sequence (G329–Y341) is completely conserved between mouse, human, and rat.
- Reconstitute with PBS before use.
Target Information
JunD is a transcription factor encoded by the JunD gene. Its transcriptional activity is regulated by phosphorylation in response to cellular stress through the JNK/SAPK pathway. Jun proteins can form dimers with Fos, ATF, and CREB family transcription factors to create the AP-1 complex, which regulates genes involved in cell growth, proliferation, differentiation, and apoptosis.
Additionally, JunD is implicated in metabolic regulation via modulation of the IGF-1 signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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