Thermo Fisher Scientific alpha-2a Adrenergic Receptor Polyclonal Antibody
Human, Mouse, Rat 시료에서 alpha-2A adrenergic receptor를 검출하는 Rabbit Polyclonal Antibody. Western blot 및 IHC에 적합하며, 고순도 항원 친화 크로마토그래피로 정제됨. PBS/BSA 버퍼에 보관하며 -20°C에서 안정적 유지.
- 카탈로그번호
- PA1048
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | View 6 publications |
| Immunohistochemistry (IHC) | - | View 6 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 2 publications |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues R(218) I Y Q I A K R R T R V P P S R R G(235) of the 3rd intracellular loop of human A2AAR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2225243 |
Product Specific Information
PA1-048 detects alpha-2A adrenergic receptor (A2AAR) from human, rat, and mouse tissues.
It has been successfully used in Western blot and immunohistochemistry procedures.
By Western blot, this antibody detects an ~45 kDa protein representing A2AAR from mouse kidney membrane preparations.
The PA1-048 immunogen is a synthetic peptide corresponding to residues R(218) I Y Q I A K R R T R V P P S R R G(235) of the 3rd intracellular loop of human A2AAR.
This sequence is completely conserved between human, mouse, rat, and porcine A2AAR.
Target Information
Alpha-2-adrenergic receptors (ADRA2A) are members of the G protein-coupled receptor superfamily.
They include three highly homologous subtypes: alpha2A, alpha2B, and alpha2C.
ADRA2A mediate the catecholamine-induced inhibition of adenylate cyclase through G protein action.
These receptors play a critical role in regulating neurotransmitter release from sympathetic nerves and adrenergic neurons in the central nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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