Thermo Fisher Scientific Tryptase Recombinant Rabbit Monoclonal Antibody (SC68-07)
Tryptase 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 IHC(P) 실험에 적합. 높은 특이성과 민감도, 로트 간 일관성 제공. Protein A 정제, 1 mg/mL 농도의 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SC68-07 |
| Immunogen | Recombinant protein within Human Mast Cell Tryptase (aa 10–275) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809516 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and expressed in HEK293 cells. Individual clones are screened to select optimal candidates for production.
Advantages include:
- Higher specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Tryptase is a serine protease primarily found in mast cells, playing a key role in immune response by activating proteins involved in inflammation and tissue repair. It also contributes to blood pressure regulation and is associated with conditions such as asthma, allergies, and cardiovascular disorders.
Structurally, tryptase forms a tetramer of identical subunits and is activated by proteolytic cleavage of its proenzyme form.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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