Thermo Fisher Scientific Phospho-Stat1 (Ser727) Recombinant Rabbit Monoclonal Antibody (Stat1S727-C6)

Applications and Tested Dilution

Product Specifications

Additional Conjugate Formats

• APC: MA5-37075
• FITC: MA5-37074
• PE: MA5-37073
• Request custom conjugation

Product Specific Information

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages include:

• Improved specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to large rabbit immune repertoire

Target Information

STAT1 (Signal Transducer and Activator of Transcription 1) is a member of the STAT family of transcription factors. It is activated by interferons (α, β, γ), EGF, PDGF, and IL-6, and regulates genes involved in cell growth, apoptosis, immune responses, and lipid metabolism.
STAT1 plays a key role in mediating cell viability in response to various stimuli and pathogens. Located on chromosome 2, STAT1 is phosphorylated by JAK kinases and translocates to the nucleus to regulate gene transcription.
Among seven STAT types (STAT1, STAT3, STAT5a, STAT5b, etc.), STAT1 shows a broad activation profile by ligands such as IFNs, gp130 family cytokines, and receptor tyrosine kinases.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.