Thermo Fisher Scientific LAP (Latency Associated Peptide) Polyclonal Antibody

Thermo Fisher Scientific LAP (Latency Associated Peptide) Polyclonal Antibody

Applications

• Western Blot (WB)

Tested Dilution

• 0.1–0.3 µg/mL

Publications

• [References not provided]

Product Specifications

Product Specific Information

This antibody is expected to recognize the region representing the latency-associated peptide.
Tested in Peptide ELISA with an antibody detection limit dilution of 1:32,000.

Target Information

TGF beta-1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines, found almost ubiquitously in tissues.
Transforming growth factor (TGF)-β is stored in the extracellular matrix as a latent complex with its prodomain. Activation of TGF-β1 requires the binding of αV integrin to an RGD sequence in the prodomain and exertion of force on this domain, which is held in the extracellular matrix by latent TGF-β binding proteins.
Latent forms are complexes of TGF-beta, an aminoterminal portion of the TGF-beta precursor designated TGF-LAP (TGF-latency associated peptide), and a specific binding protein known as LTBP.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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