Thermo Fisher Scientific JIP1 Polyclonal Antibody
JIP1 단백질을 인식하는 Thermo Fisher Scientific의 고트 폴리클로날 항체. Western blot에 최적화되어 있으며 인간 시료에 반응. 0.5 mg/mL 농도의 액상 형태로 제공되며 안정적 저장을 위한 TBS 버퍼 포함. 연구용으로만 사용 가능.
- 카탈로그번호
- PA5143314
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-DRIHYQADVRLEATE |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933953 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
The protein encoded by this gene is a regulator of pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to regulate c-Jun amino-terminal kinase (MAPK8).
This protein prevents MAPK8-mediated activation of transcription factors and decreases IL-1β and MEKK1-induced apoptosis in pancreatic beta cells.
It also functions as a DNA-binding transactivator of the glucose transporter GLUT2.
REST (RE1-silencing transcription factor) represses expression of this gene in insulin-secreting beta cells.
Mutations in this gene have been associated with type 2 diabetes susceptibility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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